A stereoselective three-component reaction: KAl(SO4)2.12H2O, an efficient and reusable catalyst for the one-pot synthesis of cis-isoquinolonic acids |
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| Authors: | Azizian Javad Mohammadi Ali A Karimi Ali R Mohammadizadeh Mohammad R |
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| Affiliation: | Department of Chemistry, Faculty of Science, Shahid Beheshti University, P.O. Box 19395-4716, Tehran, Iran. j-azizian@cc.sbu.ac.ir |
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| Abstract: | KAl(SO(4))(2).12H(2)O is found to catalyze efficiently the stereoselective one-pot three-component cyclocondensation of homophthalic anhydride, aldehydes, and amines under mild conditions to afford the corresponding cis-isoquinolonic acids in good yields. |
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