Reactions of SH-Substituted Purine Bases with Glycidol |
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Authors: | Radchenko S. I. Ratsino E. V. |
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Affiliation: | (1) Research Technological Institute of Antibiotics and Enzymes for Medicine, St. Petersburg, Russia |
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Abstract: | The regioselectivity of S-alkylation of SH-substituted purine bases with glycidol tends to grow with decreasing temperature. A procedure was developed for epoxidation of these compounds in wet liquid ammonia. The products were tested for immunostimulating activity. |
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