Electro-acupuncture promotes survival, differentiation of the bone marrow mesenchymal stem cells as well as functional recovery in the spinal cord-transected rats |
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| Authors: | Ying Ding Qing Yan Jing-Wen Ruan Yan-Qing Zhang Wen-Jie Li Yu-Jiao Zhang Yan Li Hongxin Dong Yuan-Shan Zeng |
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| Affiliation: | (1) Division of Neuroscience, Department of Histology and Embryology, 74# Zhongshan 2nd Road, Guangzhou, PR China;(2) Center for Stem Cell Biology and Tissue Engineering, 74# Zhongshan 2nd Road, Guangzhou, PR China;(3) Institute of Spinal Cord Injury, Zhongshan School of Medicine, Sun Yat-sen University, 74# Zhongshan 2nd Road, Guangzhou, PR China;(4) Department of Acupuncture of the first Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR China;(5) Department of Psychiatry and Behavioral Sciences, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, 60611-3008 Chicago, Illinois, USA |
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| Abstract: | Background Bone marrow mesenchymal stem cells (MSCs) are one of the potential tools for treatment of the spinal cord injury; however, the survival and differentiation of MSCs in an injured spinal cord still need to be improved. In the present study, we investigated whether Governor Vessel electro-acupuncture (EA) could efficiently promote bone marrow mesenchymal stem cells (MSCs) survival and differentiation, axonal regeneration and finally, functional recovery in the transected spinal cord. |
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