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Efficient synthesis of novel functionalized pyrazolo-pyranoquinoline and tetrahydrodibenzo-[1,8]naphthyridinone derivatives
Authors:Morteza Shiri  Masumeh Heydari  Vahideh Zadsirjan
Institution:Department of Chemistry, Alzahra University, Vanak, Tehran 1993893973, Iran
Abstract:The facile and efficient synthesis of 1,4-dihydropyrazolo-pyrano-2,3-b]quinoline derivatives from the reaction of 2-chloroquinoline-3-carbaldehydes and pyrazolones is described. Moreover, a one-pot method for the development of functionalized tetrahydrodibenzob,g]1,8]naphthyridinone derivatives is reported by using a three-component reaction of 2-chloroquinoline 3-carbaldehydes, pyrazolone, and enaminones catalyzed by l-proline in EtOH.
Keywords:Multicomponent reaction  2-Chloroquinoline 3-carbaldehyde  Pyrazolone derivatives  Enaminones  [1  8]Naphthyridinone  Organocatalyst
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