Determination of the relative configuration of vic-amino alcohols |
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| Authors: | Berit OlofssonPeter Somfai |
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| Institution: | Department of Chemistry, Organic Chemistry, Royal Institute of Technology, S-100 44 Stockholm, Sweden |
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| Abstract: | A large set of syn- and anti-1,2-amino alcohols has been synthesized. Upon comparison of the CH?O and CH?N 1H NMR shifts a general trend has been observed, making it possible to determine the relative configuration of 1,2-amino alcohols without derivatization or shift reagents. |
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| Keywords: | amino alcohols configuration NMR |
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