A convenient synthesis of 1-aminophosphonates from 1-hydroxyphosphonates |
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| Authors: | Babak Kaboudin |
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| Institution: | Department of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), Gava Zang, Zanjan 45195-159, Iran |
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| Abstract: | A simple, efficient, and general method has been developed for the synthesis of 1-aminophosphonates from 1-hydroxyphosphonates under solvent-free conditions using microwave irradiation. 1-Aminophosphonates were obtained in high yield and mild conditions by reaction of diethyl 1-hydroxyalkylphosphonates with amines in the presence of acidic alumina. |
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