Highly rapid and direct synthesis of monoacylated piperazine derivatives from carboxylic acids under mild conditions |
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| Authors: | BP Bandgar SS Pandit |
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| Institution: | Organic Chemistry Research Laboratory, School of Chemical Sciences, Swami Ramanand Treeth Marathwada University, Vishnupuri, Nanded 431606, India |
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| Abstract: | A series of monoacylated piperazine derivatives were obtained by the reaction of carboxylic acids with 2-chloro-4,6-dimethoxy-1,3,5-triazine in dichloromethane at room temperature. Good to excellent yields, short reaction times and mild reaction conditions are important features of this methodology. |
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