A quadruple ring-closing metathesis reaction in the synthesis of bis-spirocyclic compounds: extending the scope of metathesis chemistry |
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Authors: | Debra J. Wallace |
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Affiliation: | Department of Process Research, Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA |
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Abstract: | The first example of a quadruple ring-closing metathesis reaction is reported. The reaction of the C2 symmetric octaene 3 afforded bis-spirocyclic compounds in high yield. |
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Keywords: | ring-closing metathesis spirocycles |
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