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A quadruple ring-closing metathesis reaction in the synthesis of bis-spirocyclic compounds: extending the scope of metathesis chemistry
Authors:Debra J. Wallace
Affiliation:Department of Process Research, Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA
Abstract:The first example of a quadruple ring-closing metathesis reaction is reported. The reaction of the C2 symmetric octaene 3 afforded bis-spirocyclic compounds in high yield.
Keywords:ring-closing metathesis   spirocycles
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