Unusual O-conjugate addition reactions of β-ketoesters and 1,3-diketones to ethyl propynoate: applications to the synthesis of furans |
| |
| Authors: | Jinsung TaeKwang-Ok Kim |
| |
| Affiliation: | Department of Chemistry, Yonsei University, Seoul 120-749, South Korea |
| |
| Abstract: | Divinyl ethers were synthesized from 1,3-dicarbonyl compounds. Reactions of β-ketoesters and 1,3-diketones with ethyl propynoate in the presence of N-methylmorpholine produced unusual O-conjugate addition products in good yields. The divinyl ethers derived from 1,3-diketones were utilized for the synthesis of 2,3,5-trisubstituted furans under the standard radical cyclization conditions. |
| |
| Keywords: | O-conjugate addition 1,3-dicarbonyl compounds divinyl ethers electrophilic alkynes furans |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
