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One-pot synthesis of dihydropyrimidinones catalysed by lithium bromide: an improved procedure for the Biginelli reaction |
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| Authors: | Gourhari Maiti Pradip KunduChandrani Guin |
| Affiliation: | a Department of Chemistry, Jadavpur University, Jadavpur, Calcutta 700 032, India b Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Calcutta 700 032, India |
| Abstract: | LiBr catalyses efficiently the three component condensation reaction of an aldehyde, a β-ketoester and urea in refluxing acetonitrile to afford the corresponding dihydropyrimidinones in high yield. |
| Keywords: | dihydropyrimidinones lithium bromide Biginelli reaction |
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