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Palladium-catalyzed cross-coupling reaction of aryldioxaborolane with 2-bromo-N,N-dimethylacetamide |
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| Authors: | Ting-Yi LuCuihua Xue Fen-Tair Luo |
| Affiliation: | a Department of Chemistry and Biochemistry, National Chung Cheng University, Chia-Yi, Taiwan 621 b Institute of Chemistry, Academia Sinica, Nankang, Taipei, Taiwan 115 |
| Abstract: | A Suzuki-type cross-coupling of aryldioxaborolane with 2-bromo-N,N-dimethylacetamide in the presence of a catalytic amount of tricyclohexylphosphine as the ligand and hydroquinone as the free-radical scavenger has been demonstrated as a convenient and simple way for the synthesis of α-arylacetamide. |
| Keywords: | Suzuki coupling reactions aryldioxaborolane 2-bromo-N,N-dimethylacetamide |
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