Synthesis and properties of novel stilbene-twelve alkyl quaternary ammonium salts as antibacterial optical whitening agents |
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Authors: | Maosheng Wan Li Hua Yiwen Zeng Peifu Jiao Dengyu Xie Zhangfa Tong Guirong Wu Yongxiao Zhou Quan Tang Fuwang Mo |
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Affiliation: | 1.College of Materials and Environmental Engineering,Hezhou University,Hezhou,China;2.Department of Chemistry,Qilu Normal University,Jinan,China;3.Guangxi?Institute?of?Engineering?Technology,Nanning,China;4.School of Chemistry and Chemical Engineering,Guangxi University,Nanning,China;5.Guangxi Engineering Academy for Calcium Carbonate Industry, Co. Ltd,Guangxi University,Nanning,China |
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Abstract: | Four novel stilbene-twelve alkyl quaternary ammonium salts 5a–d were synthesized. All synthesized compounds were characterized by FT-IR, 1H-NMR and elemental analysis. Compounds 5a–d showed efficient whitening effect on cotton fiber and high fastness. Furthermore, compound 5c showed better stability to light than C186 in aqueous solution. The preliminary biological experiment demonstrated compounds 5a–d possessed significant antibacterial activities. Among them, compound 5d turned out to be the most active compound against Candida albicans with MIC50 4 μg/mL as well as E. coli with MIC50 16 μg/mL. |
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