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Synthesis and properties of novel stilbene-twelve alkyl quaternary ammonium salts as antibacterial optical whitening agents
Authors:Maosheng Wan  Li Hua  Yiwen Zeng  Peifu Jiao  Dengyu Xie  Zhangfa Tong  Guirong Wu  Yongxiao Zhou  Quan Tang  Fuwang Mo
Affiliation:1.College of Materials and Environmental Engineering,Hezhou University,Hezhou,China;2.Department of Chemistry,Qilu Normal University,Jinan,China;3.Guangxi?Institute?of?Engineering?Technology,Nanning,China;4.School of Chemistry and Chemical Engineering,Guangxi University,Nanning,China;5.Guangxi Engineering Academy for Calcium Carbonate Industry, Co. Ltd,Guangxi University,Nanning,China
Abstract:
Four novel stilbene-twelve alkyl quaternary ammonium salts 5a–d were synthesized. All synthesized compounds were characterized by FT-IR, 1H-NMR and elemental analysis. Compounds 5ad showed efficient whitening effect on cotton fiber and high fastness. Furthermore, compound 5c showed better stability to light than C186 in aqueous solution. The preliminary biological experiment demonstrated compounds 5ad possessed significant antibacterial activities. Among them, compound 5d turned out to be the most active compound against Candida albicans with MIC50 4 μg/mL as well as E. coli with MIC50 16 μg/mL.
Keywords:
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