Syntheses of 1-substituted 1,2,4-triazoles,imidazoles and benzimidazoles |
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Authors: | Abdollah Sharifian Kaykavoos Parang Hassan Zorrieh-Amirian Mehrdad Nazarinia Abbas Shafiee |
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Abstract: | Substituted 2-phenethyl-1,2,4-triazoles, 1-phenethylimidazoles 3 and 1-phenethylbenzimidazoles 5 were synthesized from the reaction of compound 8 with tri-n-butyltin hydride in good yield. The reaction of substituted-2-phenethyl halide with 1H-1,2,4-triazoles, imidazoles and benzimidazoles gave a low yield. The yield was increased by the use of substituted-2-phenethyl p-toluensulfonate. |
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