A concise and efficient synthesis of isoindolin-1-ones. New synthetic approach to the polycyclic framework of vitedoamine A期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

A concise and efficient synthesis of isoindolin-1-ones. New synthetic approach to the polycyclic framework of vitedoamine A

Authors:	Marc Lamblin Eric Deniau Pierre Grandclaudon

Affiliation:	UMR 8009 ‘Chimie Organique et Macromoléculaire’, Laboratoire de Chimie Organique Physique, Bâtiment C3(2), Université des Sciences et Technologie de Lille, F-59655 Villeneuve d'Ascq Cédex, France

Abstract:	A concise and efficient synthesis of 2,3-dihydro-1H-isoindol-1-ones based upon the Parham-type cyclization of iodinated benzyldicarbamates is reported. The synthetic potential of this approach was further emphasized by the assembly of the polycyclic framework of vitedoamine A.

Keywords:	Mitsunobu reaction Iminodicarboxylates Parham procedure Isoindolinones
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