Highly efficient ring opening reactions of epoxides with deactivated aromatic amines catalyzed by heteropoly acids in water |
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| Authors: | Najmedin Azizi |
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| Institution: | a Department of Chemistry, Sharif University of Technology, PO Box 11365-9516, Tehran, Iran
b Chemistry and Chemical Engineering Research Center of Iran, PO Box 14335-186, Tehran, Iran |
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| Abstract: | Heteropoly acid was found to be an effective and efficient catalyst for the ring opening reaction of epoxides with various aromatic amines to produce the corresponding β-amino alcohols in moderate to excellent yields in water. This method provides a new and efficient protocol in terms of mild reaction conditions, clean reaction profiles, small quantity of catalyst, and simple work-up procedure. |
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| Keywords: | Amino alcohol Aromatic amine Epoxide Heteropoly acid Atom economy Water chemistry |
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