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In vivo imaging of intrinsic optical signals in chicken retina with functional optical coherence tomography
Authors:Moayed Alireza Akhlagh  Hariri Sepideh  Choh Vivian  Bizheva Kostadinka
Affiliation:Department of Physics and Astronomy, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada.
Abstract:Visually evoked intrinsic optical signals (IOSs) were measured in vivo for the first time to our knowledge from all retina layers of the chicken retina with a combined functional optical coherence tomography and electroretinography (ERG) system. IOS traces were recorded from a small volume in the retina with 3.5 μm axial resolution and 7 ms time resolution. Comparison of the IOS and ERG traces shows a correlation between the positive and negative IOS measured from different retinal layers and the timing of the a and b waves in the ERG recording.
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