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The Synthesis of Alanine Oligopeptides |
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| Authors: | D H Lin Y S Tseng S T Chien K T Wang |
| Abstract: | The oligopeptides of alanine (penta-, deca-, and pentadeca-) were synthesized by solid phase method and new peptide-resin cleaving reagent TFA-BBr3 was used to cleave the peptides from resin-support. Penta-alanine was also synthesized by liquid phase for the comparision and FAB-Mass method was used to determine the molecular weight of penta-alanine. HPLC separation of these new oligopeptides were described. |
| Keywords: | Alanine oligopeptides TFA-BBr3 deblocking |