Synthesis of 4-substituted 5,6-diphenylmorpholine-2,3-diones with two or three chiral centers |
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| Authors: | Benito Alcaide,Carmen L pez-Mardomingo,Berta L pez-S ez,Rafael P rez-Ossorio,Joaquí n Plumet |
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| Affiliation: | Benito Alcaide,Carmen López-Mardomingo,Berta López-Sáez,Rafael Pérez-Ossorio,Joaquín Plumet |
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| Abstract: | ![]()
Chiral α-aminoalcohols obtained by stereoselective reduction of α-iminoketones have been condensed with oxalyl chloride to afford 4-substituted 5,6-diphenylmorpholine-2,3-diones having two or three chiral centers. |
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