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| Ce3+对细胞内游离Ca2+的影响 | |
| 引用本文： | 申治国,庄志雄,黄海雄,雷衡毅,杨燕生. Ce3+对细胞内游离Ca2+的影响[J]. 中国稀土学报, 2002, 20(2): 186-189 |
| 作者姓名： | 申治国 庄志雄 黄海雄 雷衡毅 杨燕生 |
| 作者单位： | 1. 深圳市卫生防疫站,广东深圳,518020 2. 中山大学化学与化学工程学院,广东广州,510275 |
| 基金项目： | 国家自然科学基金 ( 2 96710 34 )，广东省自然科学基金 ( 980 32 9)资助项目 |
| 摘 要： | 研究了Ce^3 对肝细胞和V79细胞中游离Ca^2 的影响。低浓度的Ce^3 能使肝细胞内游离Ca^2 浓度增高，高浓度的Ce^3 能使肝细胞内游离Ca^2 浓度显著升高。Ce^3 可促进细胞外Ca^2 的内流，高浓度的Ce^3 对细胞是有毒性的。 |
| 关 键 词： | 稀土 铈 游离钙 肝细胞 显微荧光术 |
| 文章编号： | 1000-4343(2002)02-0186-04 |
| 修稿时间： | 2000-11-15 |
Effect of Ce3+ on Free Cytoplasmic Calcium of Cells |
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| Abstract: | s: The effect of Ce 3+ on free cytoplasmic calcium of hepatocytes and V79 cells was studied with microfluorometry. The free cytoplasmic calcium in cells exposed to Ce 3+ increases in low dose and increases significantly in high dose. The free cytoplasmic calcium in hepatocytes exposed to Ce 3+ increases quickly at first and then decreases slowly. These results suggest that Ce 3+ might stimulate calcium inflow and enhance the free cytoplasmic calcium of cells. The result also suggestes that cerium might be toxic to hepatocytes in high dose. |
| Keywords: | rare earths cerium free cytoplasmic calcium hepatocytes microfluorometry |
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