三丁胺胺化强碱性阴离子交换树脂催化合成羧酸苄酯

用组合化学方法筛选出的对无外加碱条件下的亲核取代催化活性最高的聚合物季铵盐-三丁胺胺化强碱性阴离子交换树脂为相转移催化剂，催化合成了乙酸苄酯、丙酸苄酯、丁酸苄酯、戊酸苄酯等羧酸苄酯。讨论了各种反应条件对合成丙酸苄酯的产率的影响，并对传统合成方法进行了改进。在优化反应条件下，反应产率接近100%。

Synthesis of Benzyl Carboxylates Catalyzed by Tributyl Amine Aminating Strongly Basic Anion Exchange Resin

Macroporous tributyl amine aminating strongly basic anion exchange resin-a phase transfer catalyst with high catalytic activity for nucleophilic substitution, which was screened out via combinatorial chemistry method --was used to catalyze the nucleophilic substitution reactions for synthesis of benzyl acetate, benzyl propionate, benzyl butyrate and benzyl valerate. Influence of the reaction condition for the yield of benzyl propionate was investigated. The traditional process was improved, and the reaction condition was optimized. In the optimum reaction condition, yields of the five benzyl carboxylates was near 100%.