1. Institute of Polymers, Bulgarian Academy of Sciences, ul. Akad. G. Bonchev 103, Sofia, 1113, Bulgaria 2. Pharmaceutical Department, Sofia Medical University, ul. Dunav 2, Sofia, 1000, Bulgaria
Abstract:
IR spectroscopy and viscometry data have shown that poly(acrylic acid) and poly(methacrylic acid) form complexes with agar-agar in aqueous solutions as they do with other polysaccharides. The polyacid-agar-agar complexes are typical hydrogels. The swelling index of hydrogels based on the poly(methacrylic acid)-agar-agar complex has been found to be markedly lower than that of poly(acrylic acid)-agaragar complex. The hydrogels based on the complex of cross-linked poly(acrylic acid) with agar-agar can be of practical interest as polymeric carriers for drugs.