Pt(II) stereoisomeric complexes with serine |
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| Authors: | L. F. Krylova L. M. Matveeva G. V. Romanenko |
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| Affiliation: | (1) Novosibirsk State University, Russia;(2) International Tomographic Center, Siberian Division, Russian Academy of Sciences, Russia |
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| Abstract: | There have been synthesized Pt(II) stereoisomeric complexes with hydroxy-α-amino acid serine (SerH = NH2CH(CH2OH)COOH is α-amino-β-hydroxypropionic acid): trans-[Pt(S-SerH)2Cl2], trans-[Pt(R-SerH)(S-SerH)Cl2] with monodentately (through NH2 group ) bound SerH and cis-, trans-[Pt(R-Ser)(S-Ser)], trans-[Pt(S-Ser)2] with bidentately bound (through groups NH2 and COO) ligands (R, S is the absolute configuration of asymmetric carbon atom). The successive phases in the synthesis of Pt(II) stereoisomeric complexes with serine were studied by 195Pt NMR spectroscopy. To identificate the compounds synthesized the method of elemental analysis, IR and NMR (195Pt, 13C, 1H) spectroscopy were used. For trans-[Pt(R-Ser)(S-Ser)] the X-ray diffraction data were obtained. |
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| Keywords: | stereoisomers complexes platinum serine NMR spectra IR spectra crystalline structure |
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