Optical coherence tomography in biomedical research |
| |
Authors: | Julia Walther Maria Gaertner Peter Cimalla Anke Burkhardt Lars Kirsten Sven Meissner Edmund Koch |
| |
Institution: | (1) Dresden University of Technology, Faculty of Medicine Carl Gustav Carus, Clinical Sensoring and Monitoring, Fetscherstrasse 74, 01307 Dresden, Germany; |
| |
Abstract: | Optical coherence tomography (OCT) is a noninvasive, high-resolution, interferometric imaging modality using near-infrared
light to acquire cross-sections and three-dimensional images of the subsurface microstructure of biological specimens. Because
of rapid improvement of the acquisition speed and axial resolution of OCT over recent years, OCT is becoming increasingly
attractive for applications in biomedical research. Therefore, OCT is no longer used solely for structural investigations
of biological samples but also for functional examination, making it potentially useful in bioanalytical science. The combination
of in vivo structural and functional findings makes it possible to obtain thorough knowledge on basic physiological and pathological
processes. Advanced applications, for example, optical biopsy in visceral cavities, have been enabled by combining OCT with
established imaging modalities. This report gives an outline of the state of the art and novel trends of innovative OCT approaches
in biomedical research in which the main focus is on applications in fundamental research and pre-clinical utilization. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|