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The structure-activity relationship of inhibitors of serotonin uptake and receptor binding |
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| Authors: | Corwin Hansch Jonathan Caldwell |
| Institution: | (1) Department of Chemistry, Pomona College, 91711 Claremont, CA, U.S.A. |
| Abstract: | Summary An analysis of five different datasets of inhibitors of serotonin uptake has yielded quantitative structure/ activity relationships (QSARs) which delineate the role of steric and hydrophobic properties essential for inhibition by phenylethylamine-type analogues. |
| Keywords: | 5-Hydroxytryptamine receptors Serotonin inhibitors QSAR of serotonin inhibition and uptake |
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