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Elaboration of hydrophilic aminodextran containing submicron magnetic latex particles
Authors:Hanna Mouaziz  Sebastian Braconnot  Frédéric Ginot  Abdelhamid Elaissari
Institution:(1) CNRS-bioMérieux, ENS de Lyon, 46 allée d’Italie, 69364 Lyon Cedex 07, France;(2) bioMérieux–LETI, 17, Rue des Martyrs, 38054 Grenoble Cedex 09, France;(3) Université de Lyon, F-69622, Lyon, France; Université Lyon 1, Villeurbanne; LAGEP, UMR 5007, CNRS, CPE, 43 bd du 11 november, 69100 Villeurbanne, France
Abstract:Aminodextran containing submicron magnetic latex particles were prepared in two steps: (a) transformation of oil-in-water magnetic emulsion into structured magnetic latex particles via combination of seed and miniemulsion-like polymerization process and (b) immobilization (adsorption and chemical grafting) of prepared aminodextran onto negatively charged seed magnetic latex particles. The elaborated magnetic latex particles were characterized in terms of particle size, size distribution, morphology, surface charge density, chemical composition, magnetic properties, and also colloidal stability. The results showed that the morphology of the prepared seed magnetic latex is core–shell like and the cationic latex particles are hydrophilic and of high colloidal stability, irrespective of the aminodextran immobilization process.
Keywords:Magnetic particles  Aminodextran  Adsorption  Hydrophilic particles  Core–  shell
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