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One-pot synthesis of homotryptamines from indoles |
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| Authors: | Derek J. Denhart Ronald J. Mattson Jonathan L. Ditta John E. Macor |
| Affiliation: | Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, CT 06492-7660, USA |
| Abstract: | A method is presented for the one-pot synthesis of homotryptamines by the MacMillan reaction of indoles with acrolein followed by reductive amination. |
| Keywords: | Homotryptamine Indole Serotonin Organic catalysis |
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