Phosphoramidite approach for the synthesis of cardiolipin |
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Authors: | UMurali Krishna |
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Institution: | NeoPharm Inc., Waukegan, IL 60085, USA |
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Abstract: | A phosphoramidite approach was utilized for the first time to synthesize cardiolipin. Optically active 1,2-di-O-acyl-sn-glycerol was coupled with 2-O-protected glycerols utilizing mono- and bifunctional phosphitylating agents to yield, after final removal of protecting groups, the title compound. |
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Keywords: | Cardiolipin Phosphitylation Phosphoramidites |
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