|
|||||
|
|
Differentiation of AmpC beta-lactamase binders vs. decoys using classification <Emphasis Type="Italic">k</Emphasis>NN QSAR modeling and application of the QSAR classifier to virtual screening |
|
| Authors: | Jui-Hua Hsieh Xiang S Wang Denise Teotico Alexander Golbraikh Alexander Tropsha |
| Institution: | (1) Laboratory for Molecular Modeling, Division of Medicinal Chemistry and Natural Products and Carolina Exploratory Center for Cheminformatics Research, School of Pharmacy, University of North Carolina at Chapel Hill, CB #7360, Beard Hall, Chapel Hill, NC 27599-7360, USA;(2) Department of Pharmaceutical Chemistry and Graduate Group in Chemistry and Chemical Biology, University of California San Francisco, 1700 4th Street, San Francisco, CA 94158-2330, USA |
| Abstract: | |
| Keywords: | Binding decoys AmpC beta-lactamase kNN classification PubChem Virtual screening |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |