Enzymatic fluorination using fluoride ion generated from degradation of fluorinated materials

The recycle of fluoride ion generated from the degradation of 1-methyl-3-butylimidazolium tetrafluoroborate, diethyl methyl methoxyethylammonium tetrafluoroborate in the presence of Tris-HCl buffer solution and/or the biodegradation of fluorobenzene and benzotrifluoride, was described. The generated fluoride ion was reused to produce 5′-fluoro-5′-deoxyadenosine (5′-FDA), fluoroacetate and/or 4-fluorothreonine.