| Diorgano, Dichloro－tin （IV） Complexes of 4－X－Benzohydroxamic Acid （X=CI, OCH3）： Synthesis, Characterization, Antitumor Activity in Vitro and the Crystal Structure of trans－ [Me2Sn（L2） 2] |
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| 作者姓名： | JingHuaZHAO TaiGangLIANG QingShahLI ArmandoJ.L.Pombeiro |
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| 作者单位： | [1]SchoolofPharmaceuticalScience,ShanxiMedicalUniversity,Taiyuan030001 [2]ComplexoI,InstitutoSuperiorT6cnico,Av.RoviscoPais,1049-001Lisbon,Portugal |
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| 摘 要： | A series of diorganotin (IV) derivatives of R2SRL2 (R = Me, Et, n-Bu, ph or CI; L = Ll or L2) and their corresponding mixed-ligand complexes RESn (L1)(L2) have been prepared and the structure of trans-MeESn (L2)2 was characterized by FT-IR, ^1H, ^13C and ^ll9Sn NMR spectroscopies,MS, elemental analysis, melting points and X-ray diffIaction. The structure-activity relationships were discussed.
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| 关 键 词： | 双有机锡配合物 X射线衍射 合成 抗癌活性 二氯锡（IV）配合物 4－X－苯基羟基酰胺酸 表征 晶体结构 反式[Me2Sn（L2）2] |
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