Liposome-gold nanorod hybrids for high-resolution visualization deep in tissues |
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| Authors: | Neus Lozano Wafa' T Al-Jamal Adrian Taruttis Nicolas Beziere Neal C Burton Jeroen Van den Bossche Mariarosa Mazza Eva Herzog Vasilis Ntziachristos Kostas Kostarelos |
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| Institution: | Nanomedicine Laboratory, Centre for Drug Delivery Research, UCL School of Pharmacy, University College London , 29-39 Brunswick Square, London WC1N 1AX, U.K. |
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| Abstract: | The design of liposome-nanoparticle hybrids offers a rich toolbox for the fabrication of multifunctional modalities. A self-assembled liposome-gold nanorod hybrid vesicular system that consists of lipid-bilayer-associated gold nanorods designed to allow deep tissue detection, therapy, and monitoring in living animals using multispectral optoacoustic tomography has been fabricated and characterized in vitro and in vivo. |
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