| An efficient synthesis of substituted benzene-1,2-dicarboxaldehydes |
| |
| 引用本文： | ZHU Peter C,WANG Der-Haw,MANI Neelakandha. An efficient synthesis of substituted benzene-1,2-dicarboxaldehydes[J]. 中国科学B辑(英文版), 2007, 50(2): 249-252. DOI: 10.1007/s11426-007-0031-y |
| |
| 作者姓名： | ZHU Peter C WANG Der-Haw MANI Neelakandha |
| |
| 摘 要： | Substituted-benzene-1,2-dicarbaldehydes were synthesized by the reaction of substituted-1,2-bis(dibromomethyl) benzenes with fuming sulfuric acid,followed by hydrolysis. The yields were signifi-cantly improved by introducing solid sodium bicarbonate into the reaction mixture before hydrolysis and workup.
|
| 收稿时间： | 2006-04-11 |
| 修稿时间： | 2006-05-16 |
An efficient synthesis of substituted benzene-1,2-dicarboxaldehydes |
| |
| Zhu Peter C.,Wang Der-Haw,Lu Kaitao,Mani Neelakandha. An efficient synthesis of substituted benzene-1,2-dicarboxaldehydes[J]. Science in China(Chemistry), 2007, 50(2): 249-252. DOI: 10.1007/s11426-007-0031-y |
| |
| Authors: | Zhu Peter C. Wang Der-Haw Lu Kaitao Mani Neelakandha |
| |
| Affiliation: | 1. Advanced Sterilization Products, Johnson & Johnson, 33 Technology Drive, Irvine, CA 92618, USA
2. Pharmaceutical Research and Development La Jolla, Johnson & Johnson, 3210 Merryfield Row, San Diego, CA 92121, USA |
| |
| Abstract: | Substituted-benzene-1,2-dicarbaldehydes were synthesized by the reaction of substituted-1,2-bis(dibromomethyl) benzenes with fuming sulfuric acid,followed by hydrolysis. The yields were signifi-cantly improved by introducing solid sodium bicarbonate into the reaction mixture before hydrolysis and workup. |
| |
| Keywords: | aromatic aldehyde 1 2-bis(dibromomethyl)arene hydrolysis oxidation sodium bicarbonate fuming sulfuric acid |
| 本文献已被 万方数据 SpringerLink 等数据库收录！ |
|
