| Diastereoselective Michael Addition of (4'S)-Ethyl-3-(2',2'-Dimethyl-1',3'- dioxolan-4'-yl) acrylate with Furyl Lithium |
| |
| 作者姓名： | Dong Mei HAN Xun Tian JIANG Jian Hong CHEN Bin WANG Dong Lu BAI* Shanghai Institute of Meteria Medica Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai |
| |
| 作者单位： | Dong Mei HAN，Xun Tian JIANG，Jian Hong CHEN，Bin WANG，Dong Lu BAI* Shanghai Institute of Meteria Medica，Shanghai Institutes for Biological Sciences，Chinese Academy of Sciences，Shanghai 200031 |
| |
| 摘 要： | Recently we reported that the diastereoselective intramolecular 4+3] cycloaddition of 4 led to the formation of cycloadduct 5 as the only isolated isomer in 50% yield. The chiral C-3 of compound 4 could be used to direct the stereochemical course of 4+3] cycloaddition enabling the control of the relative stereochemistry between three contiguous asymmetric centers in adduct 51. The stereogenic center at C-3 of 4 was constructed by the asymmetric Michael addition of (, (-unsaturated ester 2 w…
|
Diastereoselective Michael Addition of (4'S)-Ethyl-3-(2',2'-Dimethyl-1',3'- dioxolan-4'-yl) acrylate with Furyl Lithium |
| |
| Dong Mei HAN,Xun Tian JIANG,Jian Hong CHEN,Bin WANG,Dong Lu BAI* Shanghai Institute of Meteria Medica,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai .Diastereoselective Michael Addition of (4''''S)-Ethyl-3-(2'''',2''''-Dimethyl-1'''',3''''- dioxolan-4''''-yl) acrylate with Furyl Lithium[J].Chinese Chemical Letters,2001(5). |
| |
| Authors: | Dong Mei HAN Xun Tian JIANG Jian Hong CHEN Bin WANG Dong Lu BAI |
| |
| Institution: | Dong Mei HAN,Xun Tian JIANG,Jian Hong CHEN,Bin WANG,Dong Lu BAI* Shanghai Institute of Meteria Medica,Shanghai Institutes for Biological Sciences,Chinese Academy of Sciences,Shanghai 200031 |
| |
| Abstract: | |
| |
| Keywords: | Michael addition configuration determination syn addition |
| 本文献已被 CNKI 等数据库收录！ |
