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Hair dye distribution in human hair by ToF-SIMS
Authors:Bo-Jung Chen  Wen-Yin Chen  Yong-Chien Ling
Institution:a Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan
b Department of Atomic Science, National Tsing Hua University, Hsinchu 30013, Taiwan
c Department of Applied Chemistry, Chung Shan Medical University, Taichung 402, Taiwan
Abstract:A single hair sample preparation protocol modified from reported method was developed and used to prepare longitudinally sectioned hair for ToF-SIMS analysis. Preliminary results demonstrate that ToF-SIMS is capable of providing molecular distribution of fragment ions from intrinsic constituents as well as external chemicals like the hair dye ingredients used in this study. The observation of pPDA and H2PO4 penetrating into the internal region of hair might initiate a renewed interest in exposure study.
Keywords:Hair dye  ToF-SIMS  Hair  p-Phenylenediamine  Sample preparation
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