Synthesis of p-aminothiophenol-embedded gold/silver core-shell nanostructures as novel SERS tags for biosensing applications期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

按检索

**Figure**
A novel SERS tag of p-Aminothiophenol (pATP) embedded Au/Ag core-shell nanostructures were prepared by adding precursor solution (AgNO₃) into the original Au nanoparticles (NPs) solution. The synthesized SERS tags, as a biosensers, were further applied to detect a biomarker protein of SS2
Synthesis of p-aminothiophenol-embedded gold/silver core-shell nanostructures as novel SERS tags for biosensing applications

Authors:	Zhihui Luo Kun Chen Donglian Lu Heyou Han Mingqiang Zou

Institution:	1. College of Science, State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, People??s Republic of China 2. Chinese Academy of Inspection and Quarantine, Beijing, 100025, People??s Republic of China

Abstract:	We describe a novel surface-enhanced Raman scattering (SERS) tag that is based on Au/Ag core-shell nanostructures embedded with p-aminothiophenol. The Au/Ag core-shell sandwich nanostructures demonstrate bright and dark stripe structure and possess very strong SERS activity. Under optimum conditions, the maximum SERS signal was obtained with a 10?nm thick Ag nanoshell, and the enhancement factor is 3.4?×?10⁴ at 1077?cm^?1. After conjugation to the antibody of muramidase releasing protein (MRP), the Au/Ag core-shell nanostructures were successfully applied to an SERS-based detection scheme for MRP based on a sandwich type of immunoassay.

Keywords:
本文献已被 SpringerLink 等数据库收录！