N4-Benzoylspermidine from Oncinotis tenuiloba: Analytical differentiation of the three isomeric N-benzoylspermidines

During the examination of extracts from Oncinotis tenuiloba STAPF a new polyamine, N⁴-benzoylsperimidine ( 8 ), was isolated. For unambiguous structure elucidation, it was transformed into the diacetyl derivative 13 , and the three possible N-benzoyl-substituted isomers of spermidine 5, 8 , and 11 together with their peracetylated derivatives 12–14 , respectively, were synthesized and identified.