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A new pinoresinol-type lignan from Ligularia kanaitizensis
Authors:Li Yun-Sen  Wang Zheng-Tao  Zhang Main  Luo Shi-De  Chen Ji-Jun
Affiliation:Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, PR China. sinodlsia@yahoo.com
Abstract:
A new pinoresinol-type Lignan, 9alpha-angloyloxypinoresinol (1), was isolated from the roots and rhizomes of Ligularia kanaitizensis (Franch.) Hand.-Mazz, in addition to a known compound, 9alpha-hydroxypinoresinol (2). The structure of this new lignan (1) was established on the basis of 1D and 2D NMR experiments. Anti-HIV-1 RT biological assay showed that 1 was inhibitory to HIV-1 RT.
Keywords:
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