A new pinoresinol-type lignan from Ligularia kanaitizensis |
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Authors: | Li Yun-Sen Wang Zheng-Tao Zhang Main Luo Shi-De Chen Ji-Jun |
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Affiliation: | Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, PR China. sinodlsia@yahoo.com |
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Abstract: | A new pinoresinol-type Lignan, 9alpha-angloyloxypinoresinol (1), was isolated from the roots and rhizomes of Ligularia kanaitizensis (Franch.) Hand.-Mazz, in addition to a known compound, 9alpha-hydroxypinoresinol (2). The structure of this new lignan (1) was established on the basis of 1D and 2D NMR experiments. Anti-HIV-1 RT biological assay showed that 1 was inhibitory to HIV-1 RT. |
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