| 5-(2-羧基苯基)-10,15,20-三苯基卟啉对氨基酸酯的分子识别模型研究 |
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| 引用本文： | 彭小彬,黄锦汪,计亮年.5-(2-羧基苯基)-10,15,20-三苯基卟啉对氨基酸酯的分子识别模型研究[J].高等学校化学学报,1999,20(1):19. |
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| 作者姓名： | 彭小彬 黄锦汪 计亮年 |
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| 作者单位： | 中山大学化学系, 广州 510275 |
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| 基金项目： | 国家自然科学基金,广州省自然科学基金,马灿安教育基金 |
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| 摘 要： | 对氨基酸及其衍生物的分子识别一直是仿生化学领域中的重要课题.以金属卟啉配合物作为主体分子对氨基酸酯的分子识别是最近几年来的热点之一15].氨基酸是蛋白质的主要组成部分,在蛋白质合成过程中,对氨基酸及其衍生物的识别是关健的一步.
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| 关 键 词： | 卟啉 氨基酸酯 分子识别新模型 |
| 收稿时间： | 1998-07-29 |
The Study of Molecular Recognition of 5(2-Carboxyphenyl)10,15,20 triphenylporphyrin to Amino Acid Esters |
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| PENG Xiao-Bin,HUANG Jin-Wang,JI Liang-Nian.The Study of Molecular Recognition of 5(2-Carboxyphenyl)10,15,20 triphenylporphyrin to Amino Acid Esters[J].Chemical Research In Chinese Universities,1999,20(1):19. |
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| Authors: | PENG Xiao-Bin HUANG Jin-Wang JI Liang-Nian |
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| Institution: | Department of Chemistry, Zhongshan University, Guangzhou, 510275 |
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| Abstract: | Using UV-Vis spectroscopic and 1HNMR methods, we have invest igated The molecu lar recognition of am ino acid esters by 5(2 carbox ypheny l)10, 15, 20 tripheny lporphyrin.The binding const ants between o-TPPCO2H and Lphenylalanine ethylester, and Lthreonine ethyl ester were obt ained.The possible recognition mode of The free porphyrin to amino acid esters has been suggested.The hydrogen bond between one of The two hydrogens of pyrroL in o-TPPCO2H and The oxygen of The carboxyl group of amino acid ester acts as one point of interaction.Another pointof interaction is The base acid interaction between amino group of amino acid ester and car boxyl group of porphyrin. |
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| Keywords: | Porphyrin Amino acid esters New mode of molecular recognition |
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