Five-membered 2,3-dioxoheterocycles: LVIII. Reaction of methyl 1-Aryl-3-aroyl-4,5-dioxo-4,5-dihydro-1H-pyrrol-2-carboxylates with substituted 1-methyl-3,4-dihydroisoquinolines. New approach to the synthesis of steroid 13-azaanalogs |
| |
Authors: | Yu N Bannikova Yu S Rozhkova Yu V Shklyaev A N Maslivets |
| |
Institution: | (1) Perm State University, Perm, 614990, Russia;(2) Institute of Problems of Chemical Physics, Russian Academy of Sciences, Chernogolovka, Russia |
| |
Abstract: | Methyl 1-aryl-3-aroyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates reacted with substituted 1-methyl-3,4-dihydroisoquinolines with the formation of substituted 3-oxo-2,3,5,6-tetra-hydropyrrolo2,1-a]-isoquinoline-2-spiro-2′-(1-aryl-3-aroyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrroles). A new approach was developed to the synthesis of 13-azagonanes, substituted benzof]pyrrolo2,1-a]isoquinoline-9-spiro-2′-pyrroles. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|