Signal amplification of streptavidin-horseradish peroxidase functionalized carbon nanotubes for amperometric detection of attomolar DNA |
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Authors: | Gao Wenchao Dong Haifeng Lei Jianping Ji Hanxu Ju Huangxian |
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Affiliation: | Key Laboratory of Analytical Chemistry for Life Science (Ministry of Education of China), Department of Chemistry, Nanjing University, Nanjing 210093, PR China. |
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Abstract: | A novel biosensing strategy for selective electrochemical detection of DNA down to the attomolar level with a linear range of 5 orders of magnitude was developed by the specific recognitions of target DNA and streptavidin to biotin labelled molecular beacon and signal amplification of streptavidin-horseradish peroxidase functionalized carbon nanotubes. |
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