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| 无溶剂无催化剂条件下二硫代氨基甲酸酯衍生物的合成研究 | |
| 引用本文： | 郭圣荣,袁艳琴,张春牛. 无溶剂无催化剂条件下二硫代氨基甲酸酯衍生物的合成研究[J]. 有机化学, 2012, 32(5): 907-914 |
| 作者姓名： | 郭圣荣 袁艳琴 张春牛 |
| 作者单位： | 丽水学院化学化工系 丽水323000 |
| 基金项目： | 浙江省自然科学基金(No.Y407240);丽水学院重点科研(No.KZ201103)资助项目~~ |
| 摘 要： | 主要研究了二硫代氨基甲酸酯衍生物的合成,将脂肪胺、CS2与α,β-不饱和羰基化合物或卤代烃在无溶剂无催化剂室温条件下,"一锅法"进行了Michael-type的加成反应,合成了二硫代氨基甲酸酯衍生物.该方法产率高,操作简单,是一种原子经济的合成方法,并可大规模地用于制药及农药方面. |
| 关 键 词： | 二硫代氨基甲酸酯 无溶剂 二硫化碳 α,β-不饱和羰基化合物 |
Highly Efficient Catalyst-Free One-Pot Synthesis of Dithiocarbamates under Solvent-Free Conditions |
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| Guo, Shengrong , Yuan, Yanqin , Zhang, Chunniu. Highly Efficient Catalyst-Free One-Pot Synthesis of Dithiocarbamates under Solvent-Free Conditions[J]. Chinese Journal of Organic Chemistry, 2012, 32(5): 907-914 | |
| Authors: | Guo Shengrong Yuan Yanqin Zhang Chunniu |
| Affiliation: | Guo,Shengrong* Yuan,Yanqin Zhang,Chunniu(Department of Chemistry,Lishui University,Lishui 323000) |
| Abstract: | A highly efficient and simple synthesis of dithiocarbamates is reported in the one-pot reaction of amines,CS2,and alkyl halides without using a catalyst under solvent-free conditions.The mild reaction conditions,high yields,and broad scope of the reaction illustrate the good synthetic utility of this method.The reaction is a highly atom-economic process for production of dithiocarbamates and can be successfully used in large amount for the pharmaceutical or agrochemical industries. |
| Keywords: | dithiocarbamates solvent-free carbon disulfide α,β-unsaturated compounds |
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