| Determination of neomycin in water samples by high performance anion chromatography with pulsed amperometric detection |
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| 作者姓名： | Bin Guan Dong Xing Yuan Environmental Science Research Center Xiamen University Xiamen China |
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| 作者单位： | Bin Guan，Dong Xing Yuan Environmental Science Research Center，Xiamen University，Xiamen 361005，China |
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| 摘 要： | A simple, fast and reliable method, using high performance anion chromatography with pulsed amperometric detection, had been developed for the analysis of neomycin in water samples. The elution and separation were carried out with an isocratic mobile phase, containing 10 mmol/L NaOH. The influence of the concentration and pH of the mobile phase on the separation and detection was investigated. A quadruple-potential waveform used for the detection was optimized. The detection limit of neomycin was down to 0.027μg/mL. The linearity of neomycin calibration curve ranged from 0.050 to 0.505μg/mL with correlation coefficient of 0.9997. R.S.D. (n = 11) was 4.0%.
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| 收稿时间： | 25 September 2006 |
Determination of neomycin in water samples by high performance anion chromatography with pulsed amperometric detection |
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| Bin Guan,Dong Xing Yuan Environmental Science Research Center,Xiamen University,Xiamen ,China.Determination of neomycin in water samples by high performance anion chromatography with pulsed amperometric detection[J].Chinese Chemical Letters,2007,18(2):201-204. |
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| Authors: | Bin Guan Dong Xing Yuan |
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| Institution: | Environmental Science Research Center, Xiamen University, Xiamen 361005, China |
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| Abstract: | A simple, fast and reliable method, using high performance anion chromatography with pulsed amperometric detection, had been developed for the analysis of neomycin in water samples. The elution and separation were carried out with an isocratic mobile phase, containing 10 mmol/L NaOH. The influence of the concentration and pH of the mobile phase on the separation and detection was investigated. A quadruple-potential waveform used for the detection was optimized. The detection limit of neomycin was down to 0.027 μg/mL. The linearity of neomycin calibration curve ranged from 0.050 to 0.505 μg/mL with correlation coefficient of 0.9997. R.S.D. (n = 11) was 4.0%. |
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| Keywords: | Neomycin High performance anion chromatography Pulsed amperometric detection |
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