Fe‐Catalyzed Cross‐Coupling Reaction of Vinylic Ethers with Aryl Grignard Reagents |
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| Authors: | Dr Takanori Iwasaki Ryo Akimoto Prof?Dr Hitoshi Kuniyasu Prof?Dr Nobuaki Kambe |
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| Institution: | Department of Applied Chemistry Graduate School of Engineering, Osaka University, Osaka, Japan |
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| Abstract: | Iron‐catalyzed cross‐coupling reaction of vinylic ethers with aryl Grignard reagents is described. The reaction proceeded at room temperature with catalytic amounts of an iron salt without the aid of costly ligands and additives. In this catalytic system, vinylic C?O bonds were preferentially cleaved over aromatic C?O bonds of aryl ethers or aryl sulfonates. |
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| Keywords: | arylation chemoselectivity C− O bond cleavage iron synthetic methods |
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