A new acylated triterpene with antimicrobial activity from the leaves of <Emphasis Type="Italic">Rauvolfia vomitoria</Emphasis> |
| |
| Authors: | Simone Veronique Fannang Victor Kuete Celine Djama Mbazoa Joseph Itbert Momo Hanh Trinh Van-Dufat Francois Tillequin Elisabeth Seguin Elizabeth Chosson Jean Wandji |
| |
| Institution: | (1) Laboratory of Synthesis and Natural Products, Department of Organic Chemistry, University of Yaounde-1, Faculty of Science, P. O. Box 812, Yaounde, Cameroon;(2) Department of Biochemistry, University of Dschang, Faculty of Science, P. O. Box 67, Dschang, Cameroon;(3) Laboratoire de Pharmacognosie de lˈUniversite Paris Descartes, UMR/CNRS No. 8638, Faculte des Sciences Biologiques et Pharmaceutiques, 4-Avenue de lˈObservatoire, 75006 Paris, France;(4) Laboratoire de Pharmacognosie, UFR de Medecine Pharmacie Rouen, 22-Bld Gambetta, 76183 Rouen Cedex 1, France; |
| |
| Abstract: | A new acylated tritrepene, 3β-hexadecanoyloxy-lup-20(29)-en-21-ol (1), along with seven known compounds, lupeol (2), betulinic acid (3), ursonic acid (4), -sitosterol (5), β-stigmasterol (6), 3-O-β-D-glucopyranosyl-β-stigmasterol (7), and palmitic acid (8), were isolated from the leaves of Rauvolfia vomitoria (Apocynaceae). Their structures were established on the basis of spectroscopic
analysis and chemical evidence. The new acylated triterpene exhibited interesting antimicrobial activity against Candida albicans
(a yeast) with the MIC value 64 μg/mL. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
