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Convenient preparation of N-8-quinolinyl benzenesultams as novel NF-κB inhibitors |
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| Authors: | Yuli Xie Yidong Liu Alison Rinderspacher Donald W Landry |
| Institution: | a Department of Medicine, Columbia University, 630 W 168th Street, New York, NY 10032, USA b Department of Physiology and Cellular Biophysics, Russ Berrie Med Sc Pav 1150 St Nicholas Ave 520, New York, NY 10032, USA |
| Abstract: | An efficient synthesis of a series of N-8-quinolinyl benzenesultams as novel NF-κB inhibitors was described via diazotization-induced cyclization of easily accessible N-8-quinolinyl-2-aminobenzenesulfonamides. |
| Keywords: | Benzenesultam NF-κB Diazotization Cyclization |
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