6-Substituted quinoline-based ratiometric two-photon fluorescent probes for biological Zn2+ detection |
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Authors: | Meng Xiangming Wang Shuxin Li Yiming Zhu Manzhou Guo Qingxiang |
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Institution: | Department of Chemistry, Anhui University, Hefei 230039, P.R. China. mengxm@ahu.edu.cn |
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Abstract: | New ratiometric two-photon fluorescent probes are developed from 6-substituted quinolines for biological Zn(2+) detection. They show large red shifts and good ratiometric responses upon Zn(2+) binding. They also exhibit high ion selectivities and large two-photon absorption cross sections at nearly 720 nm. Because the new probes are cell-permeable, they can be used to detect intracellular zinc flux under two-photon excitation. |
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