Granulated copper oxide nanocatalyst: a mild and efficient reusable catalyst for the one-pot synthesis of 4-amino-5-pyrimidinecarbonitriles under aqueous conditions |
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| Authors: | Seyed Javad Ahmadi Sodeh Sadjadi and Morteza Hosseinpour |
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| Institution: | (1) Nuclear Fuel Cycle School, Nuclear Science and Technology Research Institute, End of North Karegar Ave., P.O. Box 1439951113, Tehran, Iran;(2) Department of Energy Engineering, Sharif University of Technology, Azadi Ave., P.O. Box 113658639, Tehran, Iran; |
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| Abstract: | Abstract An efficient method for the synthesis of 4-amino-5-pyrimidinecarbonitriles by the three-component reaction of malononitrile,
aldehydes, and N-unsubstituted amidines under aqueous conditions using CuO microspheres as catalyst is reported. The catalyst
exhibited remarkable reusable activity. |
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