Photo-crosslinkable hydrogel and its biological applications |
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| Authors: | Yuting Wang Shu Zhang Jian Wang |
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| Institution: | 1. State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China;2. West China School of Stomatology, Sichuan University, Chengdu 610041, China |
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| Abstract: | In the past few years,photo-crosslinkable hydrogels have drawn a great attention in tissue engineering applications due to their high biocompatibility and extracellular matrix(ECM)-like structure.They can be easily biofabricated through exposure of a photosensitive system composed of photo-crosslinkable hydrogels,photo-initiators and other compounds such as cells and therapeutic molecules,to ultraviolet or visible light.With the development of biofabrication methods,ma ny resea rchers studied the biological applications of photo-crosslinkable hydrogels in tissue engineering,such as vascular,wound dressing and bone engineering.This review highlights the biomaterials for photo-crosslinkable hydrogels,bio fabrication techniques and their biological applications in tissue engineering.Meanwhile,the challenges and prospects of photo-crosslinkable hydrogels are discussed as well. |
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| Keywords: | Photo-crosslinkable Biomaterial Hydrogel Biofabrication Biological application |
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