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9G DNAChip: microarray based on the multiple interactions of 9 consecutive guanines
Authors:Song Keum-Soo  Nimse Satish Balasaheb  Kim Joonbae  Kim Junghoon  Nguyen Van-Thuan  Ta Van-Thao  Kim Taisun
Institution:Biometrix Technology, Inc. 202 BioVenture Plaza, Chuncheon, 200-161, Korea.
Abstract:We introduce the phenomenon of molecular recognition to immobilize oligonucleotides on AMCA slides for the production of 9G DNAChips. Facile and efficient method for the immobilization of the oligonucleotides appended with consecutive nine guanine bases is described. The 9G DNAChips shows more than 90% hybridization efficiency at 25 °C in 30 min.
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