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Isoquinoline derivatives via stepwise regioselective sp(2) and sp(3) C-H bond functionalizations
Authors:Boudiar Tarek  Sahli Zeyneb  Sundararaju Basker  Achard Mathieu  Kabouche Zahia  Doucet Henri  Bruneau Christian
Affiliation:Centre de Recherche en Biotechnologies, BPE 73, Ali Mendjli, Nouvelle Ville, 25000 Constantine, Algeria.
Abstract:
Efficient and practically attractive stepwise ruthenium- and palladium-catalyzed regioselective C-H bond functionalizations were achieved to produce 4-substituted tetrahydroisoquinoline derivatives featuring various heteroaromatic substructures in moderate to good yields. Both ruthenium- and palladium-based catalytic processes generated nontoxic and easily separable side products.
Keywords:
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