Isoquinoline derivatives via stepwise regioselective sp(2) and sp(3) C-H bond functionalizations |
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Authors: | Boudiar Tarek Sahli Zeyneb Sundararaju Basker Achard Mathieu Kabouche Zahia Doucet Henri Bruneau Christian |
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Affiliation: | Centre de Recherche en Biotechnologies, BPE 73, Ali Mendjli, Nouvelle Ville, 25000 Constantine, Algeria. |
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Abstract: | Efficient and practically attractive stepwise ruthenium- and palladium-catalyzed regioselective C-H bond functionalizations were achieved to produce 4-substituted tetrahydroisoquinoline derivatives featuring various heteroaromatic substructures in moderate to good yields. Both ruthenium- and palladium-based catalytic processes generated nontoxic and easily separable side products. |
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